Innovation Shaped By Clinical Insight
The Jack H. Skirball Center for Cardiovascular Research (SCCR) is a state-of-the-art facility dedicated to the investigation of novel concepts, treatments, and devices. Our team of interventionalists, surgeons, and pathologists guide early ideas and inventions through comprehensive research programs in order to introduce practical clinical therapies to patients. SCCR is the starting point for the technological advances that will ultimately improve the lives of those suffering from cardiovascular disease.
Translational research will be the legacy of the Skirball Center. We can help change the way people think and act about the best way to manage cardiovascular disease.
SCCR accommodates studies at every stage of the development cycle, from early concepts to protocol implementation. Whether a project requires physician specialists to help define a clinical application or highly qualified researchers to carry out a study, our partners—which include start-up enterprises, pharmaceutical firms, medical device companies, and academic research centers—benefit from our unparalleled insight and experience in the biomedical industry.
In today’s dynamic regulatory environment, SCCR’s team is committed to testing devices in environments that resemble human conditions as closely as possible. By creating uniquein vitro modeling tools, we are capable of developing unique experimental strategies designed for specific research needs. Committed to the ongoing development of experimental models that simulate human disease, scientists at SCCR have fashioned replications of complex atherosclerosis, chronic total occlusions, in-stent restenosis, vascular embolization, patent foramen ovale, myocardial ischemia and infarct, and heart failure models.
SCCR rigorously implements and maintains high standards of quality and regulatory compliance. A comprehensive system of standard operating procedures guides every aspect of SCCR’s functions regardless of whether the studies require full compliance to Good Laboratory Practice (GLP) regulations (as set forth in Code of Federal Regulation: 21 CFR Part 58). Research conducted according to GLP regulations features independent quality auditing. The SCCR team is experienced in assisting sponsors with their GLP needs, from protocol development to study conduct and final report. This assistance extends to interactions with the regulatory agencies regarding the designs of the studies and entire research programs, as well as preparation of data for submission of applications for marketing permits or permission to initiate human studies.
A Commitment to Service
SCCR is the premier destination for individuals or institutions seeking to develop new technological advances within the field of interventional cardiology. Start-up enterprises, pharmaceutical firms, medical device companies, and academic research centers will benefit from SCCR’s ability to generate protocols and research pathways, execute preclinical studies, and translate those results into human trials. Never overlooking the translational components of research, SCCR’s experts are committed to applying scientific findings to practical clinical therapies. Our group serves as a foundation for the knowledge and innovation that will continue to revolutionize interventional vascular medicine.